I'm not sure I'm following your path of thought.
Wily Introscope Workstation is not linked with Solution Manager, only the Introscope Agent is. So anything you do to user settings in Solution Manager, is not reflected to Wily Introscope Workstation. If the PC settings do not affect Wily Introscope Workstation, then there must be some local configuration for it or it is using the timezone or language of your PC. Sorry, I can't help further since I do not have Wily Introscope Workstation installed on my PC.
You maintain Wily Introscope users in the Enterprise Manager.